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1

Molecular aspects of medicine: from experimental to clinical hepatology

Dieter Häussinger, Ralf Kubitz, Roland Reinehr, Johannes G Bode, Freimut Schliess

Journal:

Molecular Aspects of Medicine

Year:

2004

Language:

english

File:

PDF, 1.66 MB

english, 2004

2

Echinokokkose-Erkrankungen

Richter, Pisa Joachim, Holtfreter, Martha, Orhun, Arzu, Müller-Stöver, Irmela, Kubitz, Ralf, Hillenbrand, Andreas, Kratzer, Wolfgang, Gräter, Tilmann, Grüner, Beate

Journal:

MMW - Fortschritte der Medizin

Year:

2015

Language:

german

File:

PDF, 869 KB

german, 2015

3

Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis

Verena Keitel, Martin Burdelski, Ulrich Warskulat, Thomas Kühlkamp, Dietrich Keppler, Dieter Häussinger, Ralf Kubitz

Journal:

Year:

2005

Language:

english

File:

PDF, 1.35 MB

english, 2005

4

Reply

Verena Keitel, Martin Burdelski, Dietrich Keppler, Dieter Häussinger, Ralf Kubitz

Journal:

Year:

2005

Language:

english

File:

PDF, 37 KB

english, 2005

5

The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells

Verena Keitel, Roland Reinehr, Petros Gatsios, Claudia Rupprecht, Boris Görg, Oliver Selbach, Dieter Häussinger, Ralf Kubitz

Journal:

Year:

2007

Language:

english

File:

PDF, 1.38 MB

english, 2007

6

The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders

Verena Keitel, Kenko Cupisti, Christoph Ullmer, Wolfram T. Knoefel, Ralf Kubitz, Dieter Häussinger

Journal:

Year:

2009

Language:

english

File:

PDF, 2.08 MB

english, 2009

7

De novo bile salt transporter antibodies as a possible cause of recurrent graft failure after liver transplantation: A novel mechanism of cholestasis

Verena Keitel, Martin Burdelski, Zsuzsanna Vojnisek, Lutz Schmitt, Dieter Häussinger, Ralf Kubitz

Journal:

Year:

2009

Language:

english

File:

PDF, 3.22 MB

english, 2009

8

Activation of rat hepatic stellate cells in culture is associated with increased sensitivity to endothelin 1

Roland M. Reinehr, Ralf Kubitz, Thorsten Peters-Regehr, Johannes G. Bode, Dieter Häussinger

Journal:

Year:

1998

Language:

english

File:

PDF, 415 KB

english, 1998

9

Organic osmolyte transport in quiescent and activated rat hepatic stellate cells (ito cells)

Thorsten Peters-Regehr, Johannes G. Bode, Ralf Kubitz, Dieter Häussinger

Journal:

Year:

1999

Language:

english

File:

PDF, 331 KB

english, 1999

10

Release of osmolytes from perfused rat liver on perivascular nerve stimulation: α-adrenergic control of osmolyte efflux from parenchymal and nonparenchymal liver cells

Stephan Vom Dahl, Johannes Georg Bode, Roland Michael Reinehr, Irmhild Mönnighoff, Ralf Kubitz, Prof. Dr. Dieter Häussinger

Journal:

Year:

1999

Language:

english

File:

PDF, 184 KB

english, 1999

11

Toponomics method for the automated quantification of membrane protein translocation

Olga Domanova, Stefan Borbe, Stefanie Mühlfeld, Martin Becker, Ralf Kubitz, Dieter Häussinger, Thomas Berlage

Journal:

BMC Bioinformatics

Year:

2011

Language:

english

File:

PDF, 676 KB

english, 2011

12

Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells

Gerd A. Kullak-Ublick, Manfred G. Ismair, Ralf Kubitz, Marcus Schmitt, Dieter Häussinger, Bruno Stieger, Bruno Hagenbuch, Peter J. Meier, Ulrich Beuers, Gustav Paumgartner

Journal:

Year:

2000

Language:

english

File:

PDF, 151 KB

english, 2000

13

Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity

Marcus Schmitt, Ralf Kubitz, Sabine Lizun, Matthias Wettstein, Dieter Häussinger

Journal:

Year:

2001

Language:

english

File:

PDF, 553 KB

english, 2001

14

Protein kinase C–dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells

Ralf Kubitz, Clemens Huth, Marcus Schmitt, Axel Horbach, Gerd Kullak-Ublick, Dieter Häussinger

Journal:

Year:

2001

Language:

english

File:

PDF, 735 KB

english, 2001

15

Heme Oxygenase-1 (HSP-32) and Heme Oxygenase-2 Induction in Neurons and Glial Cells of Cerebral Regions and Its Relation to Iron Accumulation after Focal Cortical Photothrombosis

Hans-J. Bidmon, Barbara Emde, Evelyn Oermann, Ralf Kubitz, Otto W. Witte, Karl Zilles

Journal:

Experimental Neurology

Year:

2001

Language:

english

File:

PDF, 3.34 MB

english, 2001

16

Expression and function of the bile acid receptor TGR5 in Kupffer cells

Verena Keitel, Markus Donner, Stefanie Winandy, Ralf Kubitz, Dieter Häussinger

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 1.70 MB

english, 2008

17

The histidin-loop is essential for transport activity of human MDR3. A novel mutation of MDR3 in a patient with progressive familial intrahepatic cholestasis type 3

Tamar Dzagania, Guido Engelmann, Dieter Häussinger, Lutz Schmitt, Christa Flechtenmacher, Irakli Rtskhiladze, Ralf Kubitz

Journal:

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

18

Disruption of hepatocellular tight junctions by vascular endothelial growth factor (VEGF): a novel mechanism for tumor invasion

Marcus Schmitt, Axel Horbach, Ralf Kubitz, Andrea Frilling, Dieter Häussinger

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 472 KB

english, 2004

19

Taurine supplementation induces multidrug resistance protein 2 and bile salt export pump expression in rats and prevents endotoxin-induced cholestasis

Anja Mühlfeld, Ralf Kubitz, Olaf Dransfeld, Dieter Häussinger, Matthias Wettstein

Journal:

Archives of Biochemistry and Biophysics

Year:

2003

Language:

english

File:

PDF, 333 KB

english, 2003

20

Osmosignalling in C6 glioma cells

Ralf Sinning, Freimut Schliess, Ralf Kubitz, Dieter Häussinger

Journal:

Year:

1997

Language:

english

File:

PDF, 674 KB

english, 1997

21

Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone

Ralf Kubitz, Matthias Wettstein, Ulrich Warskulat, Dieter Häussinger

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 480 KB

english, 1999

22

Involvement of CD95 (Apo-1/Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation

Markus Müschen, Ulrich Warskulat, Thorsten Peters-Regehr, Johannes G. Bode, Ralf Kubitz, Dieter Häussinger

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 259 KB

english, 1999

23

Short-term feedback regulation of bile salt uptake by bile salts in rodent liver

Mühlfeld, Stefanie, Domanova, Olga, Berlage, Thomas, Stross, Claudia, Helmer, Angelika, Keitel, Verena, Häussinger, Dieter, Kubitz, Ralf

Journal:

Year:

2012

Language:

english

File:

PDF, 970 KB

english, 2012

24

The bile salt export pump (BSEP) in health and disease

Ralf Kubitz, Carola Dröge, Jan Stindt, Katrin Weissenberger, Dieter Häussinger

Journal:

Clinics and Research in Hepatology and Gastroenterology

Year:

2012

Language:

english

File:

PDF, 916 KB

english, 2012

25

Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase

Ralf Kubitz, Gerrit Sütfels, Thomas Kühlkamp, Ralf Kölling, Dieter Häussinger

Journal:

Gastroenterology

Year:

2004

Language:

english

File:

PDF, 789 KB

english, 2004

26

Combined Mutations of Canalicular Transporter Proteins Cause Severe Intrahepatic Cholestasis of Pregnancy

Verena Keitel, Christoph Vogt, Dieter Häussinger, Ralf Kubitz

Journal:

Gastroenterology

Year:

2006

Language:

english

File:

PDF, 476 KB

english, 2006

27

[Methods in Enzymology] Phase II Conjugation Enzymes and Transport Systems Volume 400 || Inborn Errors of Biliary Canalicular Transport Systems

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

28

Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes

Ni, Yi, Lempp, Florian A., Mehrle, Stefan, Nkongolo, Shirin, Kaufman, Christina, Fälth, Maria, Stindt, Jan, Königer, Christian, Nassal, Michael, Kubitz, Ralf, Sültmann, Holger, Urban, Stephan

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 8.04 MB

english, 2014

29

Strategies to Inhibit Entry of HBV and HDV Into Hepatocytes

Urban, Stephan, Bartenschlager, Ralf, Kubitz, Ralf, Zoulim, Fabien

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 734 KB

english, 2014

30

Genetic variations of bile salt transporters

Kubitz, Ralf, Dröge, Carola, Kluge, Stefanie, Stindt, Jan, Häussinger, Dieter

Journal:

Drug Discovery Today: Technologies

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

31

Autoimmune BSEP Disease: Disease Recurrence After Liver Transplantation for Progressive Familial Intrahepatic Cholestasis

Kubitz, Ralf, Dröge, Carola, Kluge, Stefanie, Stross, Claudia, Walter, Nathalie, Keitel, Verena, Häussinger, Dieter, Stindt, Jan

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2015

Language:

english

File:

PDF, 655 KB

english, 2015

32

Conjugated bilirubin triggers anemia by inducing erythrocyte death

Lang, Elisabeth, Gatidis, Sergios, Freise, Noemi F., Bock, Hans, Kubitz, Ralf, Lauermann, Christian, Orth, Hans Martin, Klindt, Caroline, Schuier, Maximilian, Keitel, Verena, Reich, Maria, Liu, Guilai

Journal:

Year:

2015

Language:

english

File:

PDF, 733 KB

english, 2015

33

Anaphylactic shock ensuing therapeutic puncture of an echinococcal cyst

Richter, Joachim, Profis, Efim, Holtfreter, Martha C., Orhun, Arzu, Müller-Stöver, Irmela, Dedelen, Hülya, Kubitz, Ralf

Journal:

Parasitology Research

Year:

2015

Language:

english

File:

PDF, 377 KB

english, 2015

34

Severe liver fibrosis caused by Schistosoma mansoni: management and treatment with a transjugular intrahepatic portosystemic shunt

Richter, Joachim, Bode, Johannes G, Blondin, Dirk, Kircheis, Gerald, Kubitz, Ralf, Holtfreter, Martha C, Müller-Stöver, Irmela, Breuer, Matthias, Hüttig, Falk, Antoch, Gerald, Häussinger, Dieter

Journal:

The Lancet Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

35

Expression and localization of atypical PKC isoforms in liver parenchymal cells

Stross, Claudia, Keitel, Verena, Winands, Elisabeth, Häussinger, Dieter, Kubitz, Ralf

Journal:

Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 528 KB

english, 2009

36

A Mutation within the Extended X Loop Abolished Substrate-induced ATPase Activity of the Human Liver ATP-binding Cassette (ABC) Transporter MDR3

Kluth, Marianne, Stindt, Jan, Dröge, Carola, Linnemann, Doris, Kubitz, Ralf, Schmitt, Lutz

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.20 MB

english, 2015

37

Regulation of Bile Salt Export Pump mRNA Levels by Dexamethasone and Osmolarity in Cultured Rat Hepatocytes

Warskulat, Ulrich, Kubitz, Ralf, Wettstein, Matthias, Stieger, Bruno, Meier, Peter J., Häussinger, Dieter

Journal:

Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 260 KB

english, 1999

38

Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system

Kühlkamp, Thomas, Keitel, Verena, Helmer, Angelika, Häussinger, Dieter, Kubitz, Ralf

Journal:

Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 343 KB

english, 2005

39

[Methods in Enzymology] Phase II Conjugation Enzymes and Transport Systems Volume 400 || Biliary Transport Systems: Short‐Term Regulation

Year:

2005

Language:

english

File:

PDF, 456 KB

english, 2005

40

Short-Term Regulation of Canalicular Transport

HÄUSSINGER, DIETER, SCHMITT, MARCUS, WEIERGRÄBER, OLIVER, KUBITZ, RALF

Journal:

Seminars in Liver Disease

Year:

2000

Language:

english

File:

PDF, 1.99 MB

english, 2000

41

[Methods in Enzymology] Osmosensing and Osmosignaling Volume 428 || Osmoregulation of Bile Formation

Year:

2007

Language:

english

File:

PDF, 316 KB

english, 2007

42

Genetic Variants of the Bile Salt Export Pump: Inducers and Modifiers of Liver Diseases

Kubitz, Ralf, Brinkmeyer, Christoph, Sagir, Abdurrahman, Herebian, Diran, Häussinger, Dieter

Journal:

Digestive Diseases

Year:

2011

Language:

english

File:

PDF, 164 KB

english, 2011

43

Bile Acid-Induced Suicidal Erythrocyte Death

Lang, Elisabeth, Pozdeev, Vitaly I., Gatidis, Sergios, Qadri, Syed M., Häussinger, Dieter, Kubitz, Ralf, Herebian, Diran, Mayatepek, Ertan, Lang, Florian, Lang, Karl S., Lang, Philipp A.

Journal:

Cellular Physiology and Biochemistry

Year:

2016

Language:

english

File:

PDF, 762 KB

english, 2016

44

Benign Recurrent Intrahepatic Cholestasis Associated With Mutations of the Bile Salt Export Pump

Kubitz, Ralf, Keitel, Verena, Scheuring, Sybille, K??hrer, Karl, H??ussinger, Dieter

Journal:

Journal of Clinical Gastroenterology

Year:

2006

Language:

english

File:

PDF, 436 KB

english, 2006

45

Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes1

KUBITZ, Ralf, WARSKULAT, Ulrich, SCHMITT, Marcus, HÄUSSINGER, Dieter

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 309 KB

english, 1999

46

Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes1

KUBITZ, Ralf, WARSKULAT, Ulrich, SCHMITT, Marcus, HÄUSSINGER, Dieter

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 309 KB

english, 1999

47

Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide

DOMBROWSKI, Frank, KUBITZ, Ralf, CHITTATTU, Anila, WETTSTEIN, Matthias, SAHA, Nirmalendu, HÄUSSINGER, Dieter

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 239 KB

english, 2000

48

Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide

DOMBROWSKI, Frank, KUBITZ, Ralf, CHITTATTU, Anila, WETTSTEIN, Matthias, SAHA, Nirmalendu, HÄUSSINGER, Dieter

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 239 KB

english, 2000

49

High affinity anti-BSEP antibodies after liver transplantation for PFIC-2 - Successful treatment with immunoadsorption and B-cell depletion

Kubitz, Ralf, Dröge, Carola, Kluge, Stefanie, Stindt, Jan, Stross, Claudia, Häussinger, Dieter, Flechtenmacher, Christa, Wenning, Daniel, Teufel, Ulrike, Schmitt, Claus Peter, Engelmann, Guido

Journal:

Pediatric Transplantation

Year:

2016

Language:

english

File:

PDF, 411 KB

english, 2016

50

Exon-skipping and mRNA decay in human liver tissue: molecular consequences of pathogenic bile salt export pump mutations

Dröge, Carola, Schaal, Heiner, Engelmann, Guido, Wenning, Daniel, Häussinger, Dieter, Kubitz, Ralf

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.47 MB

english, 2016

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